Cancer

Overview. - Anti-hormone Therapy: Principles of Endocrine Therapy of Cancer. - Inhibition of Growth Factor Signaling by Small-Molecule Inhibitors of ErbB, Raf, and MEK. - Farnesyl Protein Transferase Inhibitors: Medicinal Chemistry, Molecular Mechanisms, and Progress in the Clinic. - Survival Signaling. - Progress in the Development of Agents to Control the Cell Cycle. - HDAC Inhibition in Cancer Therapy: An Increasingly Intriguing Tale of Chemistry, Biology and Clinical Benefit. - Development of Angiogenesis Inhibitors to Vascular Endothelial Growth Factor Receptor 2 for Cancer Therapy. - Novel Small-Molecule Inhibitors of Src Kinase for Cancer Therapy. - Bcr-Abl Kinase Inhibitors.